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Figure 2. Autophagy target protein profiles in human AD and in non-demented (control) platelet cytosols. LC3-I, LC3-II, and Atg5 proteins were probed using antibodies from MBL vendor. Beclin-1 was detected using Cell-Signaling antibody, and the p62 protein was detected using Sigma-Aldrich antibody. Each sample was analyzed three times and Mean ± SEM is presented. The protein band intensities were normalized to total protein staining. Student t-test was employed and only LC3B-1 showed significance (P ≤ 0.02). AD: Alzheimer’s disease