fig9

Figure 9. Dynamic contrast-enhanced experiments using dynamic T1 maps. A: A scheme for dynamic T1 mapping. In each T1 measurement, 8 images are acquired after 2 inversions (red line); B: pixel-wise pharmacokinetic parameters of Ktrans and Ve for a hepatic tumor (T) mimicking pancreatic tumor metastatic to the liver. Hemorrhagic necrosis caused by vascular disruption was detected in hepatic tumor 10-h after CA4P treatment. CA4P: combretastatin A4 phosphate