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    Original Article| Open Access

    Standardized protocol proposed for clinical use of L-PRF and the use of L-PRF Wound Box®

    Alessandro Crisci , Domenico Lombardi , Edda Serra , Guido Lombardi , Federica Cardillo , Michela Crisci

    Aim: The hypothesis is that the production of leukocyte and platelet-rich fibrin (L-PRF) is easy in horses without modifying human protocol, thus allowing better standardization of human protocol. In this study, the aim is to standardize the production of L-PRF in horses to direct it to human... Read more

    J Unexplored Med Data 2017;2:77-87. | doi:10.20517/2572-8180.2017.17
    Published on: 22 Nov 2017  | Viewed:2  | Downloaded:0
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    Technical Note| Open Access

    Development and applications of acquisition techniques for rat pancreatic imaging at clinical scanners

    Ting Yin , Ronald Peeters , Jie Yu , Yicheng Ni

    Rat models are frequently used in preclinical studies on the pancreatic diseases. However, non-invasive imaging of rat pancreatic models has been hampered by the small size of the pancreas and the unpredictable motion artifacts in rat abdomen. Being widely accessible and of translational... Read more

    J Unexplored Med Data 2017;2:65-76. | doi:10.20517/2572-8180.2017.19
    Published on: 14 Nov 2017  | Viewed:77  | Downloaded:3
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    Original Article| Open Access

    Analysis of resistant mutations in reverse transcriptase domain of hepatitis B virus from patients from Islamabad, Pakistan

    Majid Mahmood , Muhammad Asim Anwar

    Aim: To explore nucleoside/nucleotide analogues resistance mutations in hepatitis B virus (HBV) reverse transcriptase (RT) domain from non-responder Pakistani patients. Methods: Blood samples were taken from 20 chronic HBV patients who were non-responders to different nucleoside/nucleotide... Read more

    J Unexplored Med Data 2017;2:60-4. | doi:10.20517/2572-8180.2017.13
    Published on: 31 Oct 2017  | Viewed:46  | Downloaded:7
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    Original Article| Open Access

    Epicatechin acts synergistically with curcumin-induced cytogenotoxic effect in acute promyelocytic leukemia HL-60 cell line

    Monika A. Papież , Wirginia Krzyściak

    Aim: The low bioavailability of curcumin, a polyphenol, limits its use as an antitumor agent. Identifying mechanisms to improve the bioavailability and effectiveness of curcumin can modify utilization of other plant-derived phenolic compounds. This study was conducted with an aim to determine the... Read more

    J Unexplored Med Data 2017;2:52-9. | doi:10.20517/2572-8180.2017.12
    Published on: 25 Oct 2017  | Viewed:106  | Downloaded:8
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    Case Report| Open Access

    Crouzon syndrome: an experience of surgical intervention at Bangabandhu Sheikh Mujib Medical University, Bangladesh

    Jesmeen Morshed , Mahbub Mutanabbi , Md. Golam Hafiz

    Crouzon syndrome, also called craniofacial dysostosis is a rare autosomal dominant disease. It has a prevalence of 1 in 25,000 live births and it constitutes 4.8% of all craniosynostosis. Craniosynostosis, shallow orbits, maxillary hypoplasia, ocular proptosis and hypertelorism are the cardinal... Read more

    J Unexplored Med Data 2017;2:48-51. | doi:10.20517/2572-8180.2017.05
    Published on: 29 Aug 2017  | Viewed:494  | Downloaded:41
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    Minireview| Open Access

    Treatment of epidermal growth factor receptor mutations in non-small cell lung cancer: current role and the future perspective

    Yasar Ahmed , Harliana Yousif

    Managing advanced non-small cell lung cancer has become far more complex than in the past. This in part is due to the fact that advances in molecular oncology allow for far more refined and effective treatment options for many lung cancer patients. One of the first advances was the identification... Read more

    J Unexplored Med Data 2017;2:39-47. | doi:10.20517/2572-8180.2017.03
    Published on: 6 Jul 2017  | Viewed:1159  | Downloaded:136
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    Case Report| Open Access

    Benign leiomyoma metastasizing to the lung: a case report and a brief review of the literature

    Grazia Lazzari , Francesco Perri , Giuseppina della Vittoria Scarpati , Salvatore Pisconti , Giovanni Silvano

    The authors have investigated a rare clinical condition consisting of a benign metastatic leiomyoma (BML) spreading in the lung, in a young woman. A 42-year-old woman affected by multiple pulmonary nodules histologically diagnosed as metastases from uterine sarcoma (one of them has been resected... Read more

    J Unexplored Med Data 2017;2:34-8. | doi:10.20517/2572-8180.2017.06
    Published on: 14 Jun 2017  | Viewed:1060  | Downloaded:64
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    Original Article| Open Access

    Knowledge, awareness, and practice of forensic odontology among dental surgeons in Bhubaneswar, India

    Juber Rahman , Samapika Routray , Sudhanshu S. Mishra , Ipsita Mohanty , Neeta Mohanty , Narayan Sukla

    Aim: The aim of the study was to evaluate knowledge, awareness, and practice related to forensic odontology among dental surgeons in Bhubaneswar, East India. Methods: A blind cross-sectional study, using a questionnaire with close-ended questions, was carried out. Interns were included to assess... Read more

    J Unexplored Med Data 2017;2:26-33. | doi:10.20517/2572-8180.2017.01
    Published on: 21 May 2017  | Viewed:1642  | Downloaded:123
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    Short Communication| Open Access

    Endoscopic dual versus monotherapy in patients bleeding from high-risk peptic ulcers

    Angelo Andriulli , Silvano Loperfido , Grazia Napolitano , Rosaria Focareta , Fabio Fornari , Antonietta Garripoli , Antonio Merla , Antonio Massimo Ippolito , Pietro Leo , Riccardo Marmo

    Aim: Dual endoscopic and pharmacologic therapy is currently the standard treatment for patients with high-risk peptic ulcer bleeding. The authors assess the efficacy of dual (endoscopic and pharmacologic) therapy versus endoscopic monotherapy in reducing rates of recurrent bleeding and death in... Read more

    J Unexplored Med Data 2017;2:20-5. | doi:10.20517/2572-8180.2016.11
    Published on: 30 Mar 2017  | Viewed:562  | Downloaded:69
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    Short Communication| Open Access

    Relationship between family function and low back pain in nurses working in a tertiary hospital in North Central Nigeria

    Olawumi Olamide Iyaoromi , Musa Dankyau , Aboi Jeremiah Kutak Madaki

    Aim: The study aimed to determine the relationship between family functioning and low back pain (LBP) in nurses in a tertiary hospital in North Central Nigeria. Methods: A cross-sectional study using structured questionnaires was done among 204 randomly selected, eligible, consenting nurses in a... Read more

    J Unexplored Med Data 2017;2:16-9. | doi:10.20517/2572-8180.2016.09
    Published on: 13 Feb 2017  | Viewed:1666  | Downloaded:181
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