- Dr. Tarek Shalaby
- Senior researcher, formerly at the Department of Oncology, University Children's Hospital, 8008 Zurich, Switzerland.
Special Issue Introduction
Central nervous system tumors are a devastating illness that is considered a major cause of cancer-related morbidity. The lack of improvement in the treatment of pediatric brain tumors was mainly due to shortage of knowledge about the molecular pathogenesis of cancer. However during the recent years, advances in genomic analysis of the entire spectrum of pediatric brain tumors has led to exciting transformation as well as challenge to the current pediatric neuro-oncology diagnostic and treatment strategies. This special issue is calling for papers that present advances in the science of pediatric brain tumors, elaborate on new molecular understanding, diagnosis, therapy and outcome of brain tumors in children and highlights improvements in our understanding of pediatric brain tumors.
Scientists struggle for outstanding positive observations within the human body’s biological system that will increase our understanding of diseases. However sometimes things don’t work the way we anticipate and results where hypotheses turn out not to be true or experiments that fail to produce significant results are not published and accordingly not communicated to the scientific community. Recognizing that best evidence-based medicine should include negative studies alongside the positive ones and acknowledging the potential value and the impact it can have on sharing negative results within the academic community, this issue is welcoming both confirmatory and unconfirmatory studies in order to give a chance to negative results in pediatric CNS tumor research to be visible, shared and or cited.
Clinical trials, pilot studies, research reports, original articles, reviews and short communications.
KeywordsPediatric brain tumors, children's CNS cancer, primary brain tumors, secondary brain tumors
Submission Deadline30 Nov 2018