• Review|Open Access

    Zebrafish as screening model for detecting toxicity and drugs efficacy

    Maria Virginia Caballero , Manila Candiracci
    Embryonic and larval Danio rerio is increasingly used as a toxicological model to conduct rapid in vivo tests and developmental toxicity assays; the zebrafish features as high genetic homology to mammals, robust phenotypes and its value in high-throughput genetic and chemical screening have made... Read more
    J Unexplored Med Data 2018;3:4. | doi:10.20517/2572-8180.2017.15
    Published on: 10 Feb 2018  | Viewed:57  | Downloaded:2
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  • Original Article|Open Access

    Cytotoxic effects of tamoxifen in breast cancer cells

    Firas Hassan , Ghufran Mohammed , Gamal A. El-Hiti , Ahemd Alshanon , Emad Yousif
    Aim: To investigate the cytotoxic effects of tamoxifen on the breast cancer cell line (MCF7). Methods: The cytotoxic effects of tamoxifen on MCF7 cells were investigated using caspase-9 activity and high content screening assays. Apoptosis mechanisms following tamoxifen treatment were also... Read more
    J Unexplored Med Data 2018;3:3. | doi:10.20517/2572-8180.2017.25
    Published on: 9 Feb 2018  | Viewed:45  | Downloaded:7
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  • Review|Open Access

    Surgical outcomes of distal splenorenal shunt or liver transplantation in treatment of schistosomal refractory variceal bleeding

    Wael Mohialddin Ahmed Doush , Juhaina Ahmed Elzein
    Schistosomiasis is one of the most prevalent neglected tropical diseases, remains a serious public health problem in many developing countries in the tropics and subtropics and its pathogenesis depends on the parasite-host interaction. Periportal fibrosis of schistosomiasis complicated by portal... Read more
    J Unexplored Med Data 2018;3:2. | doi:10.20517/2572-8180.2017.18
    Published on: 30 Jan 2018  | Viewed:662  | Downloaded:14
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  • Case Report|Open Access

    A rare case of delayed chronic pneumonitis following non-medical grade silicone injections in a transgender woman

    Srilekha Sridhara , Mizba Baksh , Khatja Batool , Juel Chowdhury , Vijay Reddy , Stephanie Norwood , Sivaraman Sivaswami
    We describe a 47-year-old transgender woman with a history of non-medical grade silicone injections given by unauthorized persons 15-20 years prior to presentation who developed interstitial pneumonitis. She suffered acute exacerbations of pneumonitis, developed pulmonary fibrosis with terminal... Read more
    J Unexplored Med Data 2018;3:1. | doi:10.20517/2572-8180.2017.20
    Published on: 18 Jan 2018  | Viewed:363  | Downloaded:13
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Journal of Unexplored Medical Data Online ISSN: 2572-8180
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